[{"data":1,"prerenderedAt":131},["ShallowReactive",2],{"content-site-settings":3,"content-index-en":47},{"id":4,"extension":5,"meta":6,"stem":45,"__hash__":46},"dataFiles\u002Fdata\u002Fsite.json","json",{"en":7},{"siteDetails":8,"cookieControl":12,"siteLogo":16,"mainNav":21,"preNav":35,"stickyNav":36,"footerContent":37},{"organisationName":9,"siteName":10,"siteUrl":11},"University of Birmingham","CURLY Study Site","https:\u002F\u002Fcurly.digitrial.com\u002F",{"cookieModalTitle":13,"cookieModalText":14,"nonNecessaryCookiesUsed":15},"Cookies used on this site","This website only uses non-necessary cookies to remember where you are in the process and to learn about how people view the information. We do NOT use cookies that directly identify anyone. For the best experience please click Accept all below.",true,{"url":17,"alt":18,"width":19,"height":20},"curly-logo.svg","Home",468,172,[22,25,29,32],{"title":23,"url":24},"Taking part","\u002Ftaking-part",{"title":26,"url":27,"target":28,"external":28},"About the study","\u002Fabout\u002F",false,{"title":30,"url":31},"Resources","\u002Fresources\u002F",{"title":33,"url":34,"target":28,"external":28},"Contact","\u002Fcontact\u002F",[],[],{"footerLogo":38,"footerCol1":41,"footerCol2":42,"footerCol3":43,"additionalInfo":44},{"url":39,"alt":40,"width":19,"height":20},"curly-footer-logo.svg","CURLY Trial study logo","**Address**\\\nBirmingham Clinical Trials Unit\nPublic Health Building\nUniversity of Birmingham\nBirmingham\nB15 2TT","**Email**\\\ncurly@trials.bham.ac.uk\n\n**Telephone**\\\n0121 415 9125\n\n**Social**\\\n[Twitter](https:\u002F\u002Ftwitter.com\u002FCurlyTrial)","[Privacy policy](\u002Fprivacy)\n[Cookie policy](\u002Fcookies)\n[Accessibility statement](\u002Faccessibility)\n[Site map](\u002Fsite-map)","The CURLY Study is funded by the National Institute for Health and Care Research (Award ID: NIHR134534). The views expressed are those of the authors and are not intended to be representative of the views of the funder, sponsor or other participating organisations.\n\nThis is a digitrial site made by morph.co.uk.","data\u002Fsite","tM0pV_O_7DvWuTqghBZ_7FE8R9TbauwW4beaWWW_BeU",{"id":48,"title":49,"body":50,"description":50,"extension":5,"meta":51,"navigation":15,"path":127,"seo":128,"stem":129,"__hash__":130},"contentPages\u002Fpages\u002Findex.en.json","Home page",null,{"pageTitle":52,"pageMetadata":53,"page_content":54},"The CURLY Study",{"htmlTitle":52,"htmlDesc":52},[55,69,78,90],{"type":56,"title":57,"text":58,"image":59,"settings":64,"sectionSettings":66},"page_header","# The CURLY Study","**Cefalexin for UTIs – Right treatment Length in Young children.**\n\nA multi-centre, randomised trial to determine the optimal duration of cefalexin therapy for the treatment of febrile urinary tract infections in children.",{"url":60,"alt":61,"width":62,"height":63},"curly-header-image-1@2x.png","",1100,720,{"imgWidth":65},"half-width",{"sectionLabel":67,"customClass":68},"The TRIAL Study","page_header_bg_2",{"type":70,"text":71,"video":72,"sectionSettings":76},"text_and_video","## CURLY Patient Information Animation\n\nPlease watch our animation to find out more about the CURLY study.",{"vimeoId":73,"videoTitle":74,"videoTranscript":75,"offlineVideo":61},"827568462\u002F7c114d1bed","CURLY Participant Information Animation","The CURLY study is trying to find the best way to help children with a urine or wee infection.\n\nUrine infections are very common in children and happen when germs get into their body and make them poorly.\n\nIt can cause high temperatures, tummy pains and sickness.\n\nWe can usually stop the infection using an antibiotic called cefalexin.\n\nCefalexin is very safe and is used to treat most urine infections.\n\nSide effects are minor and rare but, in general, it is better to take antibiotics for as little time as possible.\n\nIn adults we can usually stop the infection in just a few days.\n\nDoctors are not sure if this is the same for children.\n\nThe CURLY study will find out for how long the medicine should be given to children to make them better.\n\nWe will compare medicine taken for 3, 5, 6, 8 and 10 days.\n\nThe number of days each child takes the medicine will be decided by chance, using a process called randomisation.\n\nAll children in the study will be checked to make sure the infection goes away.\n\nWe are asking lots of children with a urine infection if they want to take part.\n\nIf you decide to take part, we will ask parents to sign a consent form and older children to sign an assent form.\n\nWe will ask children and parents to fill in a questionnaire to tell us about how the infection is affecting life.\n\nWe will show families how to use an app to keep track of the amount of medicine taken and any symptoms that develop.\n\nWe will then give you the medicine to start taking at home.\n\nAfter 2 weeks you will have an appointment to check the infection has cleared.\n\nWe will again ask you to fill in a questionnaire and collect some wee in a pot.\n\nAfter 30 days you will fill in another questionnaire at home and provide another wee sample that you post back to us.\n\nAt the end of the study we will offer you a £20 gift voucher to thank you.\n\nBy taking part in the CURLY study you will help us know the best way to treat children with a urine infection in the future.\n\nThe doctors and nurses will be happy to answer any questions.",{"sectionLabel":77},"DRIFT Participant Information Animation",{"type":79,"settings":80,"title":82,"text":83,"image":84,"sectionSettings":88},"text_and_image",{"imgWidth":65,"imgPosition":81},"top","## Background","Urine infections (water infections) are very common in children. Around 1 in 10 girls and 1 in 30 boys will have had a urine infection by the age of 16 years. They can cause high temperatures, tummy pains and vomiting and can be distressing for children and parents. \n\nUrine infections are often treated with a course of antibiotic medicine for 7 - 10 days. This would usually be with an antibiotic called cefalexin. \n\nDoctors are not sure of how many days are needed for the medicine to work. In adults, just a few days of antibiotics is usually enough to treat the infection, but we are not sure if this is the same for children. Shorter courses of antibiotics may have several benefits over longer courses: \n\n1. Fewer side-effects, like diarrhoea and vomiting.\n2. A lower risk of developing 'bad bacteria', which don't respond to normal antibiotics.\n3. Children might start to feel better sooner.",{"url":85,"alt":61,"width":86,"height":87},"curly-header-image-3@2x.png",920,600,{"sectionLabel":89},"Background",{"type":91,"settings":92,"cards":95,"sectionSettings":125},"text_and_cards",{"headerLevel":93,"headerFontSize":93,"maxCardsPerRow":93,"wholeClickable":15,"numberedCards":28,"alignCards":94,"alignCardContent":94},"3","left",[96,107,116],{"type":97,"image":98,"title":102,"summary":103,"links":104},"card_image_text",{"url":99,"width":100,"height":101,"alt":61},"curly-card-image-1.svg",1000,640,"Taking Part","Find out more about taking part in the study",[105],{"title":106,"url":24,"external":28,"target":28},"Go to 'Taking Part'",{"type":97,"image":108,"title":110,"summary":111,"links":112},{"url":109,"width":100,"height":101,"alt":61},"curly-card-image-2.svg","About the Study","Learn more about the study",[113],{"title":114,"url":115},"Got to 'About the Study'","\u002Fabout",{"type":97,"image":117,"title":119,"summary":120,"links":121},{"url":118,"width":100,"height":101},"curly-card-image-3.svg","Contact Us","Get in touch with the study team",[122],{"title":123,"url":124},"Get in touch","\u002Fcontact",{"sectionLabel":126},"Benefits of screening for type 1 diabetes:","\u002Fpages\u002Findex.en",{"title":49},"pages\u002Findex.en","00bkZZJrTYANHR5c6e01kuy4leLVLhdpxVIe6z7SOTQ",1791212950683]