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Taking part

This page explains the CURLY Study for people who might be interested in joining.

General information

We want to recruit children aged between 3 months and 11 years with urine infections to take part in our trial.

Families who agree to join the study will be split into 5 even groups. Depending on what group the child is in, they will take the antibiotics for 3, 5, 6, 8, or 10 days.

Parents will report the child's symptoms using email or smartphones. We will check the symptoms carefully to make sure that the treatment is working well. We will also see the child for a follow-up appointment 3 weeks after the start of treatment and collect a third urine sample to test for bacteria at 5 weeks. Doctors will prescribe more antibiotics during the trial if the treatment is not working well.

At the end of the study, we will know how many days of antibiotic children with urine infections should take to get better.

To make sure people learn about this new information we will talk to other doctors and people in the NHS who write national guidelines. Parents who have helped design this study will help deliver the study and the final message to parents and children.

CURLY Information for Patients

If you are considering taking part in the CURLY Study, please follow the link below to open the CURLY Participant Information Tool. Here you can view the key information needed to decide whether to take part.

CURLY Trial study logo

Birmingham Clinical Trials Unit
Public Health Building
University of Birmingham
B15 2TT

[email protected]

0121 415 9125


The CURLY Study is funded by the National Institute for Health and Care Research (Award ID: NIHR134534). The views expressed are those of the authors and are not intended to be representative of the views of the funder, sponsor or other participating organisations.

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